ABN293

Anti-Prohibitin Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Prohibitin
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human
• Speziesreaktivität (Voraussage durch Homologie): rat (based on 100% sequence homology), canine (based on 100% sequence homology), bovine (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI-Hinterlegungsnummer: NP_002625
• UniProt-Hinterlegungsnummer: P35232
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PHB(5245)

Beschreibung

Allgemeine Beschreibung

Prohibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.

Spezifität

Other homologies: Mouse (86% sequence homology).

This antibody recognizes Prohibitin near the N-Terminus.

Immunogen

KLH-conjugated linear peptide corresponding to human Prohibitin near the N-Terminus.

Anwendung

Detect Prohibitin using this rabbit polyclonal antibody, Anti-Prohibitin Antibody validated for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:100-500 dilution from a representative lot detected Prohibitin in human kidney and human ileum tissue.

Qualität

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Prohibitin in 10 µg of human liver tissue lysate.

Zielbeschreibung

~32 kDa observed

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable