ABD28

Anti-Rfx6 Antibody

serum, from rabbit

• Synonym(e): DNA-binding protein RFX6, Regulatory factor X 6, Regulatory factor X domain-containing protein 1
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Antikörperform: serum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Speziesreaktivität: mouse
• Methode(n): immunohistochemistry: suitable
• NCBI-Hinterlegungsnummer: NP_001152861
• UniProt-Hinterlegungsnummer: Q8C7R7
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: mouse ... Rfx6(320995)

Beschreibung

Allgemeine Beschreibung

Rfx6 (regulatory factor X 6) is a winged-helix transcription factor that is essential for development and seems to be located exclusively in the pancreatic islets. It has been associated with endoderm development, specifically, and the differentiation of islet cells. Since insulin production happens in the beta-cells of pancreatic islets, Rfx6 may be used clinically to treat diabetes. Recently, Rfx6 function has been found to change over time and gets restricted to endocrine cells at later stages. Mitchell-Riley syndrome is thought to stem from a Rfx6 mutation.

Immunogen

GST-tagged recombinant protein corresponding to mouse Rfx6.

Anwendung

Research Category
Stammzellforschung

Research Sub Category
Transkriptionsfaktoren

Anti-Rfx6 Antibody is a Rabbit Polyclonal Antibody for detection of Rfx6 also known as DNA-binding protein RFX6, Regulatory factor X 6 & has been validated in IHC.

Qualität

Evaluated by Immunohistochemistry in mouse embryo pancreas tissue.

Immunohistochemistry Analysis: 1:400 dilution of this antibody detected Rfx6 in mouse embryo pancreas tissue.

Zielbeschreibung

102 kDa calculated. Additional isoforms at 59 and 73 kDa have also been reported.

Physikalische Form

Unpurified

Rabbit polyclonal serum containing 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Hinweis zur Analyse

Control
Mouse embryo pancreas tissue

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1