8.56057

H-Pro-2-ClTrt resin

Novabiochem^®

• Synonym(e): Chlorotrityl Resin
• UNSPSC-Code: 12352209
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 400
• Produktlinie: Novabiochem^®
• Form: beads
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal proline amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in DCM. The use of this resin enables the synthesis of peptides containing C-terminal Pro without risk of diketopiperazine formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Anwendung

• B Yakimova et al. Reported the use of H-Pro-2-ClTrt resin in the synthesis of short peptides with potential ACE inhibitory activity (B Yakimova, et al., 2021).
• S Wang et al. Detailed the use of H-Pro-2-ClTrt resin in a study on aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase (S Wang, et al., 2022).
• LP Vu et al. Described the use of H-Pro-2-ClTrt resin in the synthesis of inhibitors for serine proteases (LP Vu, et al., 2022).

Verlinkung

Replaces: 04-12-2805

Hinweis zur Analyse

Farbe (visuell): schwach gelb bis beige
Aussehen der Substanz (visuell): Kügelchen
Identität (der Beladung): entspricht
Beladung (Photometrische Bestimmung des Fmoc-Chromophores nach Abspaltung vom Fmoc-Leu beladenen Harz.): 0.30 - 1.10 mmol/g
Aufquellvolumen (in DMF): chargenspezifischer Wert
Die Polymermatrix ist Copoly (Styrol - 1% DVB) 200 - 400 mesh

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable