8.21092

Tetrahydrofurfurylalkohol-Polyethylenglycolether (Glycofurol)

for synthesis

• Synonym(e): Tetrahydrofurfurylalkohol-Polyethylenglycolether (Glycofurol), Glycofurol
• CAS-Nummer: 31692-85-0
• MDL-Nummer: MFCD00801146
• UNSPSC-Code: 12352104

Eigenschaften

• Qualitätsniveau: 200
• Form: liquid
• bp: 176 °C/40 hPa
• Dichte: 1.08 g/cm³ at 20 °C
• Lagertemp.: 2-30°C
• InChI: 1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
• InChIKey: CTPDSKVQLSDPLC-UHFFFAOYSA-N

Beschreibung

Anwendung

• Biodegradable microparticle production: A novel green process employing CO2 medium was developed for the production of biodegradable microparticles encapsulating TGF-beta1, utilizing tetrahydrofurfuryl alcohol polyethylene glycol ether, enhancing the sustained release properties of the therapeutic proteins (Swed et al., 2015).


• Nanocarrier devices for targeted drug delivery: Tetrahydrofurfuryl alcohol polyethylene glycol ether was utilized in the formulation of photosensitizer-loaded nanocarrier devices, bridging laboratory and large-scale production, and demonstrating potential in targeted drug delivery systems (Beyer et al., 2015).


• Cardiac tissue-engineering: In cardiac tissue engineering, tetrahydrofurfuryl alcohol polyethylene glycol ether was incorporated into a thermosensitive hydrogel for releasing growth factors from pharmacologically active microcarriers, presenting a biomimetic 3D scaffold that supports cardiac cell growth (Karam et al., 2014).


• Enhanced pharmacokinetics in drug delivery: A self-microemulsifying drug delivery system incorporating tetrahydrofurfuryl alcohol polyethylene glycol ether demonstrated improved pharmacokinetics for tacrolimus, suggesting its efficacy in bioavailability enhancement (von Suesskind-Schwendi et al., 2013).

Hinweis zur Analyse

Dichte (d 20 °C/ 4 °C): 1,080 - 1,090
Identität (IR): entspricht

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 275.0 °F - closed cup
• Flammpunkt (°C): 135 °C - closed cup