8.20128

Saccharin

for synthesis

• Synonym(e): Saccharin
• Empirische Formel (Hill-System): C₇H₅NO₃S
• CAS-Nummer: 81-07-2
• Molekulargewicht: 183.18
• MDL-Nummer: MFCD00005866
• UNSPSC-Code: 12352115
• EG-Index-Nummer: 201-321-0
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.0% (acidimetric)
• Form: crystals
• mp (Schmelzpunkt): 228-230 °C
• Lagertemp.: 2-30°C
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• InChIKey: CVHZOJJKTDOEJC-UHFFFAOYSA-N

Beschreibung

Anwendung

• Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).


• Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).

Hinweis zur Analyse

Gehalt (acidimetrisch): ≥ 98.0 %
Schmelzbereich (unterer Wert): ≥ 226 °C
Schmelzbereich (oberer Wert): ≤ 230 °C
Identität (IR): entspricht

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable