489350

L-(–)-Norepinephrine-(+)-bitartrate

α,β-Adrenergic agonist.

• Synonym(e): L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline
• Empirische Formel (Hill-System): C₈H₁₁NO₃ · C₄H₆O₆ · H₂O
• CAS-Nummer: 108341-18-0
• Molekulargewicht: 337.28
• MDL-Nummer: MFCD00150449
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Beschreibung: Merck USA index - 14, 6695
• Assay: ≥97% (LC/MS)
• Form: crystalline solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated
• Farbe: white
• Löslichkeit: water: 1 mg/mL
• Versandbedingung: ambient
• Lagertemp.: 2-8°C
• SMILES String: NC[C@H](O)c1cc(c(cc1)O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O
• InChI: 1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
• InChIKey: LNBCGLZYLJMGKP-LUDZCAPTSA-N

Beschreibung

Allgemeine Beschreibung

α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
α,β-Adrenergic agonist

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Angaben zur Herstellung

Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.

Rekonstituierung

Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Yang, H., et al. 1996. Hypertension 27, 1277.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300 + H310
• P-Sätze: P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Oral
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable