407654
Interleukin-6, Mouse, Recombinant, E. coli
Synonym(e):
rmIL-6
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About This Item
UNSPSC-Code:
12352202
NACRES:
NA.41
Empfohlene Produkte
Assay
≥97% (SDS-PAGE)
Qualitätsniveau
Form
lyophilized
Hersteller/Markenname
Calbiochem®
Lagerbedingungen
OK to freeze
Verunreinigungen
≤1 EU/μg Endotoxin (EU/μg IL-6)
Versandbedingung
ambient
Lagertemp.
−70°C
Allgemeine Beschreibung
Recombinant, mouse interleukin-6 expressed in E. coli. Stimulates the production of acute phase proteins by hepatocytes. Induces growth and differentiation of B cells, hepatocytes, keratinocytes, and nerve cells.
Recombinant, mouse interleukin-6 expressed in E. coli. Stimulates the production of acute phase proteins by hepatocytes. Induces growth and differentiation of B cells, hepatocytes, keratinocytes, and nerve cells. Does not inhibit any significant activity on human cells.
Biochem./physiol. Wirkung
ED₅₀ = 20-60 pg/ml as measured in a cell proliferation assay with a factor-dependent plasmacytoma cell line
Warnhinweis
Toxicity: Irritant (B)
Physikalische Form
Lyophilized from sterile-filtered 50 mM NaOAc, 1 mM EDTA, 5% trehalose, 50 µg BSA/µg IL-6 pH 4.0.
Rekonstituierung
Following reconstitution, aliquot and freeze (-20°C or -70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 3 months at -20°C or -70°C or for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Reconstitute to a concentration of ≥10 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
Sonstige Hinweise
Matsuda, T., et al. 1994. Biochem. Biophys. Res. Commun.202, 637.
Rechtliche Hinweise
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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T Matsuda et al.
Biochemical and biophysical research communications, 202(1), 637-642 (1994-07-15)
Interleukin-6 (IL-6) signal is transduced through a membrane glycoprotein gp130, which associates with the IL-6 receptor alpha chain (IL-6R alpha) in the presence of IL-6. We prepared monoclonal antibodies (mAbs) specific to murine gp130 by immunizing rats and hamsters with
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