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Merck
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Key Documents

14-679-M

Sigma-Aldrich

HIPK1 Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555. For use in Kinase Assays.

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About This Item

UNSPSC-Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32

Biologische Quelle

human

Qualitätsniveau

100
300

Rekombinant

expressed in baculovirus infected Sf21 cells

Mol-Gew.

Mw 49.6 kDa

Hersteller/Markenname

Upstate®

Methode(n)

activity assay: suitable (kinase)

NCBI-Hinterlegungsnummer

NM_152696.3
NM_181358.1
NM_198268.1
NM_198269.1

UniProt-Hinterlegungsnummer

Q86Z02

Angaben zum Gen

human ... HIPK1(204851)

Allgemeine Beschreibung

N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555.
Product Source: HIPK1 expressed by baculovirus in Sf21 cells.

Anwendung

Research Category
Stoffwechsel
Research Sub Category
Obesity

Metabolic Disorders

Biochem./physiol. Wirkung

Protein Target: HIPK1
Target Sub-Family: CMGC

Qualität

routinely evaluated by phosphorylation of MBP (13-104).

Physikalische Form

Ni2+/NTA-agarose

Lagerung und Haltbarkeit

6 months at -70°C from date of shipment

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Jae J Song et al.
The Journal of biological chemistry, 278(47), 47245-47252 (2003-09-12)
Overexpression of JNK binding domain inhibited glucose deprivation-induced JNK1 activation, relocalization of Daxx from the nucleus to the cytoplasm, and apoptosis signal-regulating kinase 1 (ASK1) oligomerization in human prostate adenocarcinoma DU-145 cells. However, SB203580, a p38 inhibitor, did not prevent
Y H Kim et al.
The Journal of biological chemistry, 273(40), 25875-25879 (1998-09-25)
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed
Jeffrey A Ecsedy et al.
Molecular and cellular biology, 23(3), 950-960 (2003-01-17)
We describe an interaction between homeodomain-interacting protein kinase 1 (HIPK1) and Daxx, two transcriptional regulators important in transducing growth-regulatory signals. We demonstrate that HIPK1 is ubiquitously expressed in mice and humans and localizes predominantly to the nucleus. Daxx normally resides

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