14-444-M
PKC θ Protein, active, 10 µg
Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.
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About This Item
UNSPSC-Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
human
Qualitätsniveau
Rekombinant
expressed in Sf21 cells
Mol-Gew.
Mw 83 kDa
Hersteller/Markenname
Upstate®
Methode(n)
activity assay: suitable (kinase)
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Angaben zum Gen
human ... PRKCQ(5588)
Allgemeine Beschreibung
Product Source: expressed in Sf21 cells
Recombinant full-length human PKC theta with a C-terminal 6His-tag
PKC Lipid activator (Catalog # 20-133) is required for use.
PKC Lipid activator (Catalog # 20-133) is required for use.
Biochem./physiol. Wirkung
Protein Target: PKCθ
Target Sub-Family: AGC
Qualität
routinely evaluated by phosphorylation of Histone H1 substrate in vitro
Physikalische Form
immobilized nickel affinity chromatography
Lagerung und Haltbarkeit
6 months at -70 °C
Sonstige Hinweise
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Skin Sens. 1
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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G Baier et al.
The Journal of biological chemistry, 268(7), 4997-5004 (1993-03-05)
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types and, to date, the cloning of seven mammalian PKC genes encoding eight distinct isoforms has
B Bauer et al.
The Journal of biological chemistry, 276(34), 31627-31634 (2001-06-19)
Protein kinase C theta (PKC theta) is known to induce NF-kappa B, an essential transcriptional element in T cell receptor/CD28-mediated interleukin-2 production but also T cell survival. Here we provide evidence that PKC theta is physically and functionally coupled to
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