1.16177

LiChrospher^® 100 RP-18 (5 µm) HPLC Columns

HPLC sorbent

• Synonym(e): TM=["LiChrospher"] C18 sorbent for HPLC
• UNSPSC-Code: 41115709
• NACRES: SB.52

Eigenschaften

• product name: LiChrospher^® 100 RP-18 (5 µm),
• Materialien: stainless steel column
• Agentur: suitable for USP L1
• Produktlinie: LiChrospher^®
• Leistungsmerkmale: endcapped: no
• Verpackung: 1 ea of
• Kennzeichnungsgrad: 21% Carbon loading
• Parameter: 60 °C max. temp.
• Methode(n): HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• Oberflächenbereich: 350 m²/g
• Matrix: fully porous particle
• Aktive Matrixgruppe: C18 bonding phase
• Partikelgröße: 5 μm
• Porengröße: 100 Å pore size
• operating pH range: 2-7.5
• Schüttdichte: 200‑400 kg/m³
• Trenntechnik: reversed phase
• Lagertemp.: no temp limit

Beschreibung

Allgemeine Beschreibung

LiChrospher^® RP-18 ist ein zuverlässiger und vielseitiger, traditionell hergestellter, sphärischer Kieselgelträger mit C-18-Umkehrphaseneigenschaften. Er eignet sich besonders gut für die Trennung von neutralen, sauren und schwach basischen Verbindungen.

Anwendung

• Fast Determination of a Novel Iron Chelate Prototype Used as a Fertilizer by Liquid Chromatography Coupled to a Diode Array Detector.: This study explores the use of LiChrospher^® 100 RP-18 (5 µm) for the rapid analysis of a new iron chelate fertilizer, showcasing its effectiveness in agricultural applications (Valverde et al., 2021).


• Application of Chemometric Approach for Development and Validation of High-Performance Liquid Chromatography Method for Estimation of Ropinirole Hydrochloride.: The research utilizes LiChrospher^® 100 RP-18 (5 µm) for the quantification of ropinirole in pharmaceutical formulations, highlighting its precision and robustness (Fatima et al., 2019).


• Quantification of Alprenolol and Propranolol in Human Plasma Using a Two-Dimensional Liquid Chromatography (2D-LC).: This paper demonstrates the application of LiChrospher^® 100 RP-18 (5 µm) in clinical settings for the analysis of beta-blockers in plasma, indicating its utility in pharmacokinetics (Gonçalves et al., 2017).


• Ultrasound-Assisted Surfactant-Enhanced Emulsification Micro-Extraction Followed by HPLC for Determination of Preservatives in Water, Beverages, and Personal Care Products.: The study highlights the use of LiChrospher^® 100 RP-18 (5 µm) for environmental and quality control analyses, demonstrating its versatility in various matrices (Jan-E et al., 2017).


• Development and Validation of Stability-Indicating HPLC Method for Determination of Cefpirome Sulfate.: This research focuses on the stability testing of cefpirome using LiChrospher^® 100 RP-18 (5 µm), emphasizing its reliability for pharmaceutical quality control (Zalewski et al., 2014).

Hinweis zur Analyse

Anwendungstechnischer Test: entspricht
Druck: ≤ 35 bar
Theoretische Bodenzahl (N/m) (Toluol): ≥ 60000
Stabilitätstest (Leistung): entspricht
Trennfaktor (Acetophenon/Phenol, Selektivitätstest): 2,05–2,25
Trennfaktor (Acetophenon/Zimtsäure, Selektivitätstest): 1,24–1,37
k′-Wert (Toluol): 13,0–18,0

Rechtliche Hinweise

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable