1.11714

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

for biochemistry

• Synonym(e): 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Thiazolyl blue, MTT
• Empirische Formel (Hill-System): C₁₈H₁₆BrN₅S
• CAS-Nummer: 298-93-1
• Molekulargewicht: 414.32
• MDL-Nummer: MFCD00011964
• UNSPSC-Code: 12352107
• EG-Index-Nummer: 206-069-5
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Form: solid
• mp (Schmelzpunkt): 195 °C
• Löslichkeit: 10 g/L
• Lagertemp.: 2-30°C
• InChI: 1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
• InChIKey: AZKSAVLVSZKNRD-UHFFFAOYSA-M

Beschreibung

Anwendung

<ul>
<li><strong>Anal Biochem, 2017</strong>: Comparison of MTT and Neutral Red assays to assess cell viability in the presence of copper compounds, highlighting the versatility and sensitivity of the MTT assay in cytotoxicity testing (Gomez Perez et al., 2017).</li>
<li><strong>Indian J Pharmacol, 2016</strong>: Evaluation of the cytotoxic potential of various Indian fruit peels on liver cancer cells (HepG2) using MTT assay, providing insights into natural product research and potential anticancer properties (Garg et al., 2016).</li>
<li><strong>ACS Appl Mater Interfaces, 2015</strong>: Application in the real-time evaluation of live cancer cells, combining surface plasmon resonance and electrochemical methodologies with MTT assays for enhanced accuracy in viability testing (Wu et al., 2015).</li>
</ul>

Hinweis zur Analyse

Gehalt (argentometrisch): ≥ 98
Identität (IR-Spektrum): entspricht
Spez. Extinktion E1%/1cm (242 nm; 0.001 %; 1 cm; Methanol): 480 - 530
Schwermetalle (als Pb): ≤ 0.001 %
Sulfatasche: ≤ 0.5 %

Sicherheitshinweise

• Piktogramme: GHS07,GHS08
• Signalwort: Warning
• H-Sätze: H315 - H319 - H335 - H341
• P-Sätze: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable