1.05552

TLC-Aluminiumblätter, Zellulose

pkg of 25 sheets, sheet L × W 20 cm × 20 cm, aluminum support

• Synonym(e): Thin-layer chromatography cellulose plates
• UNSPSC-Code: 41115711
• NACRES: NB.21

Eigenschaften

• Materialien: aluminum support; cellulose matrix
• Qualitätsniveau: 100
• Leistungsmerkmale: binder Organic Polymer; fluorescent indicator: no
• Verpackung: pkg of 25 sheets
• Methode(n): thin layer chromatography (TLC): suitable
• Schichtdicke: 70-110 μm
• Blatt L × B: 20 cm × 20 cm
• Lagertemp.: 2-30°C

Beschreibung

Allgemeine Beschreibung

25 Aluminiumplatten 20 x 20 cm

Unsere Cellulose-Platten werden zur Untersuchung von polaren Stoffen eingesetzt. Als organisches Sorptionsmittel ist Cellulose ideal für die Trennung hydrophiler Stoffe mittels Verteilungschromatographie. Zu den typischen Anwendungen zählt die Analyse von Aminosäuren, Kohlenhydraten und Phosphaten sowie von Nukleinsäure und ihren Derivaten. Die Cellulose-Platten sind in zwei Qualitätsklassen erhältlich: TLC für konventionelle und HPTLC für anspruchsvolle Hochleistungstrennungen.

Anwendung

• Simple and sensitive determination of sulfites in Chinese herbal teas by ultrahigh-performance liquid chromatography tandem mass spectrometry: This study highlights the utilization of HILIC technology for the sensitive analysis of sulfites in herbal teas, demonstrating the versatility of SeQuant^® ZIC-HILIC^™ columns in maintaining the stability and enhancing the sensitivity of such measurements (Yang et al., 2022).


• Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: The research applies HILIC methods to effectively measure antibiotics in various biological fluids, providing an example of the column′s applicability in pharmacokinetic research studies (Pandey et al., 2020).


• Application of Hydrophilic Interaction Liquid Chromatography for the Quantification of Flavonoids in Genista tinctoria Extract: Demonstrates the use of HILIC for the effective separation and quantification of flavonoids, showcasing the column′s efficiency in handling complex herbal matrices (Sentkowska et al., 2016).


• HPLC-UV method development for fentanyl determination in rat plasma and its application to elucidate pharmacokinetic behavior after i.p. administration to rats: This study underlines the adaptability of SeQuant^® ZIC-HILIC^™ in developing methods for the forensic and pharmacological analysis of potent opioids in biological samples (Almousa et al., 2011).


• Hydrophilic interaction liquid chromatography/positive ion electrospray ionization mass spectrometry method for the quantification of perindopril and its main metabolite in human plasma: Highlights the application of HILIC in tandem with mass spectrometry for the analysis of drugs and their metabolites, emphasizing the column′s role in enhancing detection sensitivities (Georgakakou et al., 2010).

Verlinkung

Ersetzt: 5552-7; 5552

Hinweis zur Analyse

Schichtdicke: 70–110 µm
Dickenschwankung pro Platte: ≤ 30 µm
Aminosäuretest
hRf-Werte
- L-Serin, Aminosäuretest:
20–30
- L-Threonin, Aminosäuretest: 29–36
- L-Alanin, Aminosäuretest: 30–40
- L-Methionin, Aminosäuretest: 49–60
- L-Phenylalanin, Aminosäuretest: 59–70
- L-Leucin, Aminosäuretest: 66–76
An einer Folie ermittelter typischer Wert
Eluent: 1-Butanol/Aceton/Essigsäure/Wasser (35/35/7/23 v/v/v/v), zweifach entwickelt

Rechtliche Hinweise

SeQuant is a registered trademark of Merck KGaA, Darmstadt, Germany

ZIC-HILIC is a trademark of Merck KGaA, Darmstadt, Germany