09-796

Anti-PADI4 Antibody, CT

from rabbit

• Synonym(e): HL-60 PAD, PADI-H protein, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase, Protein-arginine deiminase type-4
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: saturated ammonium sulfate (SAS) precipitated
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Speziesreaktivität: human
• Methode(n): ELISA: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_036519
• UniProt-Hinterlegungsnummer: Q9UM07
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PADI4(23569)

Beschreibung

Allgemeine Beschreibung

PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Spezifität

The antibody recognizes PADI4 at and around the C-terminus.

Immunogen

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen

Research Sub Category
Histone

Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA.

ELISA: A 1:1000 dilution of a previous lot was used on ELISA.

Qualität

Evaluated by western blot on HEK293 cell lysate.

Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate.

Zielbeschreibung

~74 kDa

Physikalische Form

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

Lagerung und Haltbarkeit

Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC

Hinweis zur Analyse

Control
HEK293 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable