05-1946

Anti-USP7 Antibody, clone 1G7

clone 1G7, from mouse

• Synonym(e): ubiquitin specific peptidase 7 (herpes virus-associated), Ubiquitin-specific-processing protease 7, ubiquitin specific protease 7 (herpes virus-associated), Herpesvirus-associated ubiquitin-specific protease, Herpes virus-associated ubiquitin-specific pr
• UNSPSC-Code: 12352203
• eCl@ss: 32160702

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: 1G7, monoclonal
• Speziesreaktivität: human
• Speziesreaktivität (Voraussage durch Homologie): mouse (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NP_003461.2
• UniProt-Hinterlegungsnummer: Q93009
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... USP7(7874)

Beschreibung

Allgemeine Beschreibung

Ubiquitin carboxyl-terminal hydrolase 7 (USP7) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates.[Saridakis, 2005] Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, Ubiquitin carboxyl-terminal hydrolase 7 activity generally stabilizes its substrate proteins. Ubiquitin carboxyl-terminal hydrolase 7 is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.[Canning, 2004]

Spezifität

This antibody recognizes USP7.

Immunogen

Histadine-tagged recombinant protein corresponding to human USP7.

Anwendung

This Anti-USP7 Antibody, clone 1G7 is validated for use in WB, IP, IH for the detection of USP7.

Qualität

Evaluated by Western Blot in HeLa lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected USP7 on 10 µg of HeLa cell lysate.

Zielbeschreibung

~ 128kDa Observed

Physikalische Form

Format: Purified

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable