04-1470

Anti-OX40L (CD252) Antibody, clone RM134L

clone RM134L, from rat

• Synonym(e): Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rat
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: RM134L, monoclonal
• Speziesreaktivität: mouse
• Methode(n): flow cytometry: suitable; immunohistochemistry: suitable
• Isotyp: IgG2bκ
• NCBI-Hinterlegungsnummer: NP_033478
• UniProt-Hinterlegungsnummer: P43488
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: mouse ... Tnfsf4(22164)

Beschreibung

Allgemeine Beschreibung

OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases.

Spezifität

This antibody recognizes the extracellular domain of OX40L.

Immunogen

Mouse OX40L cDNA-transfected NRK cells

Anwendung

Anti-OX40L (CD252) Antibody, clone RM134L detects level of OX40L (CD252) & has been published & validated for use in Flow Cytometry & IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.)

Qualität

Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.

Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells.

Zielbeschreibung

22 kDa calculated

Physikalische Form

Format: Purified

Hinweis zur Analyse

Control
Mouse OX40L/L5178Y cells

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable