N-902

Nortriptylin-D₃ -hydrochlorid -Lösung

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₁₉D₃H₁₈N · HCl
• CAS-Nummer: 136765-48-5
• Molekulargewicht: 302.86
• MDL-Nummer: MFCD00198172
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329818692
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Qualitätsniveau: 300
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 100 μg/mL in methanol (as free base)
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: [2H]C([2H])([2H])NCCC=C1C2=C(C=CC=C2)CCC3=C1C=CC=C3.[H]Cl
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H/i1D3;
• InChIKey: SHAYBENGXDALFF-NIIDSAIPSA-N

Beschreibung

Allgemeine Beschreibung

Nortriptyline is a second generation tricyclic antidepressant (TCA) marketed under trade names such as Sensoval, Aventyl^®, and Pamelor^® for treatment of major depression. Nortriptyline is also an active metabolite of the TCA amitriptyline. This certified Snap-N-Spike^® Solution is suitable as an internal standard for quantitation of nortriptyline levels by LC/MS or GC/MS in clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, or medication monitoring applications.

Anwendung

• Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).: This study demonstrates a robust method for the quantification of tricyclic antidepressants, including Nortriptyline-D3, using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. The approach offers precise measurement essential for pharmacokinetic and neuropharmacological research, aligning with the interests of researchers in pharma and biotech focused on antidepressant metabolism studies (Clarke et al., 2016).

Rechtliche Hinweise

Aventyl is a registered trademark of Eli Lilly and Co.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pamelor is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup