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N-031

Supelco

Norfentanyl oxalate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C14H20N2O · C2H2O4
CAS-Nummer:
1211527-24-0
Molekulargewicht:
322.36
EG-Nummer:
200-659-6
MDL-Nummer:
MFCD08272799
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329818426
NACRES:
NA.24

Qualität

certified reference material

Qualitätsniveau

300

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

Konzentration

1.0 mg/mL in methanol (as free base)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

forensics and toxicology

Format

single component solution

Lagertemp.

−20°C

SMILES String

OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2

InChI

1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)

InChIKey

OLFNESLXXQCODF-UHFFFAOYSA-N

Allgemeine Beschreibung

Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. This Certified Spiking Solution® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology and forensic analysis to urine drug testing and pain prescription monitoring.

Rechtliche Hinweise

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup

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Ming Jin et al.
Journal of analytical toxicology, 29(7), 590-598 (2006-01-20)
Pharmacogenomics, the study on genetic contributions to drug action may help in certifying fentanyl toxicity. Fentanyl is used clinically as an adjunct to surgical anesthesia and for chronic pain management. Its toxicity may be partially due to cytochrome P450 (CYP)
Claudia F Clavijo et al.
Journal of separation science, 34(24), 3568-3577 (2011-09-15)
Preterm and term neonates often require surgical procedures and analgesia. However, our knowledge about neonatal pharmacokinetics of fentanyl, the most commonly used drug for these procedures, and its metabolites is still incomplete. To facilitate pharmacokinetic studies of fentanyl and its
Ruth Verplaetse et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(22), 1987-1996 (2010-06-15)
Fentanyl and its major metabolite norfentanyl often occur in low doses in biological samples. Therefore, a highly sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method has been developed and fully validated. Sample preparation was performed on a mixed-mode cation exchange
Evan D Kharasch et al.
Anesthesiology, 101(3), 738-743 (2004-08-27)
Cancer pain is primarily a problem of older persons. Oral transmucosal fentanyl citrate (OTF) was developed to provide rapid analgesia and is the first drug specifically approved for treating breakthrough cancer pain. Fentanyl in OTF is absorbed across the oral
N-H Huynh et al.
Journal of pharmaceutical and biomedical analysis, 37(5), 1095-1100 (2005-05-03)
Fentanyl, a potent analgesic drug, has traditionally been used intravenously in surgical or diagnostic operations. Formulations with fentanyl in oral transmucosal delivery system and in transdermal depot-patch have also been developed against breakthrough pain in cancer patients. In this report
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