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M-138

Supelco

Mephedrone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C11H16ClNO
CAS-Nummer:
1189726-22-4
Molekulargewicht:
213.70
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

Konzentration

1.0 mg/mL in methanol (as free base)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

forensics and toxicology

Format

single component solution

Lagertemp.

−20°C

InChI

1S/C11H15NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,12H,1-3H3;1H

InChIKey

DLQZFTUKJGRPLZ-UHFFFAOYSA-N

Allgemeine Beschreibung

Mephedrone, also known as 4-methylmethcathinone, is a synthetic stimulant of the amphetamine and cathinone classes. Significant abuse of this new recreational drug has been reported within the last year in the UK; Sweden; and Toronto, Canada with confiscation of the drug in states including Oregon.

Anwendung


  • Nanotube-based Sensors for Drug Molecule Discrimination: Mephedrone is studied for its interaction with nanotube-based sensors, enhancing the discrimination of drug molecules. This research is critical for developing new technologies in forensic science and drug abuse monitoring, providing high accuracy in identifying psychoactive substances (Algharagholy et al., 2023).

  • Environmental Monitoring of New Psychoactive Substances: Analytical methods including mephedrone have been developed for the simultaneous determination of 56 new psychoactive substances in surface water. This application is vital for environmental monitoring and understanding the ecological impact of synthetic cathinones, ensuring water safety and public health (Atasoy Aydin et al., 2023).

  • Supramolecular Hosts for In Vivo Sequestration: Research on supramolecular hosts capable of sequestering mephedrone and other stimulants like methamphetamine and fentanyl in vivo, provides significant advancements in therapeutic approaches for drug addiction and overdose treatment. This study paves the way for novel detoxification strategies using chemical sequestrants (Brockett et al., 2023).

  • SERS Substrates for Clinical Applications: Mephedrone has been examined in the development of ultrasensitive portable Surface-Enhanced Raman Scattering (SERS) substrates. These substrates are designed for rapid and precise clinical diagnostics, showcasing the potential of mephedrone in enhancing bioanalytical methods (Lin et al., 2023).

  • Forensic Differentiation of Isomers: Portable near-infrared spectroscopy has been utilized for the isomeric differentiation of mephedrone among new psychoactive substances. This technology is essential for law enforcement and forensic applications, providing a quick and non-destructive means to distinguish between drug isomers in field conditions (Kranenburg et al., 2022).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Anwendung

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Beschreibung
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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Priscilla B Pail et al.
Neurotoxicology, 50, 71-80 (2015-08-10)
Mephedrone and methedrone are cathinone-related compounds, which act as non-selective substrates for monoamine transporters, facilitating a neurotransmitter release. We compared the acute pharmacological effects of mephedrone and methedrone, attempting to further evaluate the action mechanisms of methedrone by responsibly and

Artikel

Improved GC/MS Derivatization Techniques for Analysis of New Designer Drugs: Methylone, Ethylone, Butylone, Mephedrone, and Methedrone

As new “bath salt” drugs such as methylone, ethylone, mephedrone, butylone and other methcathinone analogs increase in popularity, toxicologists require native and labeled certified reference materials to accurately identify and quantify the new compounds in patient samples.

Isolation and LC-MS Characterization of Illicit Bath Salts in Urine

The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Fast Analysis

Separation of Butylone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Ethylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Mephedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Evaluation of LCMSMS Deuterium Scrambling in Clinically Significant Small Molecules

LC-MS/MS is a powerful tool that brings numerous benefits to the clinical sample analysis arena. However, due to the complexity of the instrumentation there are some unique challenges that also accompany these benefits. Even following sample extraction and cleanup, matrix effects from the samples can cause interferences or impact ionization efficiency.

Protokolle

LC/MS (TOF) Analysis of Illicit Bath Salts in Urine on Ascentis® Express HILIC after Solid Phase Extraction (SPE) using Supel™-Select SCX

Separation of 3,4-Methylenedioxypyrovalerone HCl (MDPV) solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Buphedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 3-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Butylone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Ethylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 4-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Mephedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Chromatograms

application for HPLC

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