M-011

(±)-MDMA-D₅ -Lösung

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(e): (±)-3,4-Methylen-dioxy-methamphetamin-d₅
• Empirische Formel (Hill-System): C₁₁D₅H₁₀NO₂
• CAS-Nummer: 136765-43-0
• Molekulargewicht: 198.27
• EG-Nummer: 200-659-6
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
• Konzentration: 100 μg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): forensics and toxicology
• Format: single component solution
• Lagertemp.: 2-8°C
• SMILES String: [2H]C(c1ccc2OCOc2c1)C([2H])(C)NC([2H])([2H])[2H]
• InChI: 1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3/i2D3,5D,8D
• InChIKey: SHXWCVYOXRDMCX-RMOCDOLISA-N

Beschreibung

Allgemeine Beschreibung

MDMA ist eine illegale Droge, besser bekannt unter Szenenamen wie „Ecstasy“, „E“, „X“ oder „XTC“. MDMA ist ein Analogon der Phenethylamin- und Amphetamin-Klassen und wird wegen seiner euphorisierenden und psychedelischen Wirkung missbraucht. Dieser als stabil gekennzeichnete interne Standard eignet sich für die Quantifizierung des MDMA-Gehalts in Urin, Serum oder Plasma mittels LC/MS oder GC/MS in der Urin-Drogenkontrolle, klinischen Toxikologie, forensischen Analytik oder für Isotopenverdünnungsmethoden.

Anwendung

• MDMA-D₅ internal standard for forensic toxicology: A study demonstrated the utilization of MDMA-D₅ as an internal standard in the detection of nutmeg abuse through gas chromatography-mass spectrometric screening of urine, showcasing its critical role in toxicological analysis (Neukamm et al., 2020).


• Stable isotope-labeled MDMA for pharmacokinetic studies: Research highlighted a one-step derivatization-extraction method using MDMA-D₅ for rapid analysis of amphetamines and cathinones in oral fluid by GC-MS, emphasizing its utility in fast and efficient drug monitoring (Mohamed, 2017).


• Synthetic MDMA derivative for forensic toxicology: A publication discussed the identification and quantification of synthetic cathinones in hair by LC-MS/MS, where MDMA-D₅ served as a reference material, underlining its importance in long-term substance abuse monitoring (Alvarez et al., 2017).


• Deuterated MDMA reference material for biochemistry research: A study utilized hollow-fiber liquid-phase microextraction of amphetamine-type stimulants in human hair samples, employing MDMA-D₅ to enhance analytical precision and reliability in biochemical assays (do Nascimento Pantaleão et al., 2012).


• Quantitative mass spectrometry MDMA: Evidence of mephedrone chronic abuse was provided through hair analysis using GC/MS, with MDMA-D₅ being crucial for establishing methodological accuracy and drug profiling (Martin et al., 2012).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup