D-010

1,2-Dinitroglycerin -Lösung

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₃H₆N₂O₇
• CAS-Nummer: 621-65-8
• Molekulargewicht: 182.09
• EG-Nummer: 200-835-2
• MDL-Nummer: MFCD00661060
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329798580
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 1.0 mg/mL in acetonitrile
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: OC[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O
• InChI: 1S/C3H6N2O7/c6-1-3(12-5(9)10)2-11-4(7)8/h3,6H,1-2H2
• InChIKey: GFVHBTOOPNJKLV-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1,2-Dinitroglycerin ist ein wichtiger Plasmametabolit des pharmazeutischen Vasodilators Nitroglycerin. Diese Certified Spiking Solution^® ist geeignet für Anwendungen in der pharmazeutischen Forschung oder der klinischen Toxikologie, die auf Chromatographie oder Massenspektrometrie basieren. Nitroglycerin wird zur Behandlung von Herzerkrankungen wie Angina und chronischer Herzinsuffizienz eingesetzt.

Anwendung

• Pharmacokinetics of transdermal nitroglycerin: Research demonstrates the pharmacokinetic profiling of nitroglycerin and its metabolites from a transdermal delivery system, including 1,2-Dinitroglycerin, which contributes to its sustained release and absorption characteristics. This study supports its use in controlled drug delivery applications (Auclair et al., 1998).



• Nitroglycerin metabolism research: Analytical techniques for studying the metabolism of nitroglycerin, including the role of 1,2-Dinitroglycerin, were detailed, highlighting methods for examining nitrite and glutathione interactions. This research aids in understanding the metabolic pathways and implications of nitroglycerin derivatives in pharmacology (Curry et al., 1987).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302 + H312 + H332,H319
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 35.6 °F - closed cup
• Flammpunkt (°C): 2 °C - closed cup