880124X

DSPE-PEG(2000) Folate

Avanti Research^™ - A Croda Brand 880124X

• Synonym(e): 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000] (ammonium salt):methanol (9:1)
• CAS-Nummer: 1236288-25-7
• MDL-Nummer: MFCD28143627
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: liquid
• Verpackung: pkg of 1 × 1 mL (880124X-10mg); pkg of 1 × 1 mL (880124X-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 880124X
• Konzentration: 1 mg/mL (880124X-1mg); 10 mg/mL (880124X-10mg)
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

DSPE-PEG(2000) Folate, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000], is a functionalized PEG lipid. This lipid is added into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for numerous solid tumors and myeloid leukemias. Folate targeted drug delivery is used an effective therapy for the treatment and imaging of various cancers and inflammatory diseases. Folate conjugates with low molecular weight and high binding affinity for folate receptors (FR) on cell surface deliver a variety of molecular complexes such as protein toxins, immune stimulants, chemotherapeutic agents, liposomes, nanoparticles, and imaging agents to pathologic cells without affecting normal tissues.

Anwendung

DSPE-PEG(2000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000]) may be used in preparation of folate-conjugated liposomes and folate-modified microvesicles (MVs).

Verpackung

5 mL Clear Glass Sealed Ampule (880124X-10mg)

5 mL Clear Glass Sealed Ampule (880124X-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H226,H302,H315,H319,H331,H336,H351,H361d,H371,H372
• P-Sätze: P210 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P311
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3
• Zielorgane: Eyes,Central nervous system, Liver,Kidney, Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 80.6 °F
• Flammpunkt (°C): 27 °C