880123X

DSPE-PEG(5000) Folate

Avanti Research^™ - A Croda Brand 880123X

• Synonym(e): 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt):methanol (9:1)
• CAS-Nummer: 1236288-25-7
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: liquid
• Verpackung: pkg of 1 × 1 mL (880123X-500ug)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 880123X
• Konzentration: 0.5 mg/mL (880123X-500ug)
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP([O-])(OCCNC([(OCH2CH2)113]NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

Beschreibung

Allgemeine Beschreibung

DSPE-PEG(5000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) is incorporated into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for various cancers and myeloid leukemias. Folate targeted drug delivery is potentially used for the treatment and imaging of several cancers and inflammatory diseases. Folate conjugates are small molecules having high binding affinity for folate receptors (FR) on cell surface. Therefore, they have an ability to deliver a variety of molecular complexes to pathologic cells without affecting normal tissues.

Anwendung

DSPE-PEG(5000) Folate may be used:

• in preparation of folate functionalized nanoparticles (NPs)
• in synthesis of BTPEPBI-containing nanoparticles
• in preparation of paclitaxel loaded folate modified lipid-shell and polymer-core nanoparticles (FLPNPs)

Verpackung

5 mL Clear Glass Sealed Ampule (880123X-500ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H370,H372
• P-Sätze: P201 - P260 - P264 - P280 - P308 + P311 - P403 + P233
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable