850563P
Avanti
Bicelle Kit
Avanti Research™ - A Croda Brand
Synonym(e):
Bicelle Creation Kit for High-quality Membrane Protein Crystal Production
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Alle Fotos(1)
About This Item
UNSPSC-Code:
12352211
NACRES:
NA.28
Empfohlene Produkte
Assay
99% (TLC)
Form
powder
Hersteller/Markenname
Avanti Research™ - A Croda Brand
Versandbedingung
dry ice
Lagertemp.
−20°C
Allgemeine Beschreibung
Bicelle kit contains 200mg of dimyristoylphosphatidylcholine (DMPC), 200mg of dimyristoylphosphatidylglycerol (DMPG), 1g of 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate (CHAPS) and 1g of 3-(cholamidopropyl)dimethylammonio-2-hydroxy-1-propane-sulfonate (CHAPSO). Bicelle is a discoidal lipid aggregate. A bicelle consists of a planar bilayer at the center made of long-chain phospholipids, which are encircled by a detergent layer. The planar bilayer is generally composed of DMPC, which may have phospholipids such as (DMPG) for alteration of charge of the membrane. The detergent layer is composed of bile salt derivative, such as CHAPSO.
The bicelle kit is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
Biochem./physiol. Wirkung
Bicelles acts as membrane mimetics and facilitate membrane-associated biomolecules study.
Verpackung
20ML Clear Glass Screw Cap Vial for each component (850563P-1EA)
Package contains 200MG of DMPC, 200MG of DMPG, 1G of CHAPS, and 1G of CHAPSO
Rechtliche Hinweise
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Crystallization of Membrane Proteins in Bicelles
Sayeh Agah; Salem Faham
Methods in Molecular Biology, 914 (2012)
K J Glover et al.
Biophysical journal, 81(4), 2163-2171 (2001-09-22)
Several complementary physical techniques have been used to characterize the aggregate structures formed in solutions containing dimyristoylphosphatidylcholine (DMPC)/dihexanoylphosphatidylcholine (DHPC) at ratios of < or =0.5 and to establish their morphology and lipid organization as that of bicelles. (31)P NMR studies
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