850446C

14:0-18:0 PC

1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, chloroform

• Synonym(e): 1-tetradecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine; MSPC; PC(14:0/18:0)
• Empirische Formel (Hill-System): C₄₀H₈₀NO₈P
• CAS-Nummer: 76343-22-1
• Molekulargewicht: 734.04
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: liquid
• Verpackung: pkg of 1 × 2.5 mL (850446C-25mg); pkg of 2 × 4 mL (850446C-200mg)
• Hersteller/Markenname: Avanti Polar Lipids 850446C
• Konzentration: 10 mg/mL (850446C-25mg); 25 mg/mL (850446C-200mg)
• Lipid-Typ: cardiolipins; phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• InChI: 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
• InChIKey: TYAQXZHDAGZOEO-KXQOOQHDSA-N

Beschreibung

Allgemeine Beschreibung

Phosphatidylcholine (PC) is one of the most important constituent of colon′s mucosal layer. 14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetrical lipid.

Anwendung

14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:

• in lipid bilayers to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
• as an asymmetrical lipid in liposomes to study the impact of bilayer area and lipid geometry on the design of liposomes as liposomal solubilizing agents
• to prepare a low temperature-sensitive liposome encapsulating thrombolytics to assess thrombolytic activity following hyperthermia

Biochem./physiol. Wirkung

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Verpackung

5 mL Clear Glass Sealed Ampule (850446C-200mg)

5 mL Clear Glass Sealed Ampule (850446C-25mg)

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
• P-Sätze: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): does not flash
• Flammpunkt (°C): does not flash