W387509

Methylsulfoxid

≥99%

• Synonym(e): Dimethylsulfoxid, DMSO, Methylsulfoxid
• Lineare Formel: (CH₃)₂SO
• CAS-Nummer: 67-68-5
• Molekulargewicht: 78.13
• FEMA-Nummer: 3875
• Beilstein: 506008
• EG-Nummer: 200-664-3
• MDL-Nummer: MFCD00002089
• UNSPSC-Code: 12191502
• PubChem Substanz-ID: 24901911
• Flavis-Nummer: 12.175

Eigenschaften

• Biologische Quelle: synthetic
• Qualität: Halal
• Agentur: meets purity specifications of JECFA
• Dampfdichte: 2.7 (vs air)
• Dampfdruck: 0.42 mmHg ( 20 °C)
• Assay: ≥99%
• Selbstzündungstemp.: 573 °F
• Haltbarkeit: Expiration date period - 5 years
• Expl.-Gr.: 42 %, 63 °F
• Farbe: colorless
• Brechungsindex: n20/D 1.479 (lit.)
• bp: 189 °C (lit.); 189 °C
• mp (Schmelzpunkt): 16-19 °C (lit.)
• Löslichkeit: water: miscible
• Dichte: 1.10 g/mL (lit.)
• Anwendung(en): flavors and fragrances
• Dokumentation: see Safety & Documentation for available documents
• Nahrungsmittelallergen: no known allergens
• Organoleptisch: butter; sulfurous
• SMILES String: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Dimethyl sulfoxide (DMSO) is a hygroscopic, high polarity amphiphilic solvent with an ability to dissolve many compounds. Cytotoxic study of DMSO on the pulp tissue repair-related activity of odontoblast-like cells showed it produced minor effects. Along with phosphorus pentaoxide it participates in the oxidation of carbohydrates to afford aldosuloses and aldosiduloses. DMSO participates in the oxidation of some partially-acetylated carbohydrates followed by elimination to afford unsaturated, derivatives. Solubility of amylose and amylopectin in DMSO has been evaluated.

Anwendung

DMSO has been used to prepare the DMSO-phosphate buffer solution, which was used to dissolve the selective ET_B (ET = endothelin) receptor antagonist in a study. It has been used for the preparation of nysatin solution.

Dimethyl sulfoxide may be used in the synthesis of the following:

• α, β−Unsaturated carbonyl sugar derivatives.
• Conversion of secondary bromides or olefins to bromohydrin.
• Synthesis of α-hydroxycarbonyls from corresponding ketones.

Vorsicht

Unterkühlt leicht und schmilzt langsam bei Raumtemperatur. Das verfestigte Produkt kann durch Erwärmen auf Raumtemperatur wieder verflüssigt werden, ohne dabei geschädigt zu werden.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 188.6 °F - closed cup
• Flammpunkt (°C): 87 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)