P57204

Pyridazin

98%

• Synonym(e): 1,2-Diazabenzene, 1,2-Diazine, o-Diazine
• Empirische Formel (Hill-System): C₄H₄N₂
• CAS-Nummer: 289-80-5
• Molekulargewicht: 80.09
• Beilstein: 103906
• EG-Nummer: 206-025-5
• MDL-Nummer: MFCD00006463
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24898697
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• Brechungsindex: n20/D 1.524 (lit.)
• bp: 208 °C (lit.)
• mp (Schmelzpunkt): −8 °C (lit.)
• Dichte: 1.103 g/mL at 25 °C (lit.)
• SMILES String: c1ccnnc1
• InChI: 1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H
• InChIKey: PBMFSQRYOILNGV-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.

Anwendung

Pyridazine can be used:

• As a building block to synthesize N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine derivatives as GSK-3 inhibitors.
• As a starting material in the synthesis of pharmacologically important pyrrolo[1,2-b]pyridazine derivatives.
• To prepare 1-(6-ethoxy-6-oxohexyl)pyridazin-1-ium bromide and 1-(2-bromoacetyl) pyridazinium bromide ionic liquids as corrosion inhibitors of steel under acidic conditions.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 185.0 °F - closed cup
• Flammpunkt (°C): 85 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)