E35400

2-Methylacetoacetat-Ethyl

90%

• Synonym(e): Ethyl 2-methyl-3-oxobutanoate
• Lineare Formel: CH₃COCH(CH₃)CO₂C₂H₅
• CAS-Nummer: 609-14-3
• Molekulargewicht: 144.17
• Beilstein: 1071742
• EG-Nummer: 210-179-9
• MDL-Nummer: MFCD00009164
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24894520
• NACRES: NA.22

Eigenschaften

• Assay: 90%
• Form: liquid
• Brechungsindex: n20/D 1.418 (lit.)
• bp: 187 °C (lit.)
• Dichte: 1.019 g/mL at 25 °C (lit.)
• SMILES String: CCOC(=O)C(C)C(C)=O
• InChI: 1S/C7H12O3/c1-4-10-7(9)5(2)6(3)8/h5H,4H2,1-3H3
• InChIKey: FNENWZWNOPCZGK-UHFFFAOYSA-N

Beschreibung

Anwendung

• Ethyl 2-methylacetoacetate is used as a substrate in the rhenium-catalyzed synthesis of multisubstituted aromatic compounds.
• It can be employed in the synthesis of coumarin derivatives via Pechmann condensation.
• It undergoes dehydration to yield conjugated alkynyl and allenyl esters.
• It is also used in the total synthesis of chlorotonil A, yangjinhualine A, (+)- and (−)-saudin.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 145.4 °F - closed cup
• Flammpunkt (°C): 63 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter