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D2388

Sigma-Aldrich

Dimethyl-3,3′-Dithiopropionimidat -dihydrochlorid

powder

Synonym(e):

DTBP, Dimethyl-3,3′-dithiodipropionimidat -dihydrochlorid, Wang-Richards’ Reagens -dihydrochlorid

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About This Item

Empirische Formel (Hill-System):
C8H16N2O2S2 · 2HCl
CAS-Nummer:
38285-78-8
Molekulargewicht:
309.28
MDL-Nummer:
MFCD00043245
UNSPSC-Code:
12352116
PubChem Substanz-ID:
57654084
NACRES:
NA.22

Form

powder

Eignung der Reaktion

reagent type: cross-linking reagent

Löslichkeit

H2O: 50 mg/mL

Lagertemp.

2-8°C

SMILES String

Cl.Cl.COC(=N)CCSSCCC(=N)OC

InChI

1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H

InChIKey

CQBCVFHLZAVNPF-UHFFFAOYSA-N

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Verwandte Kategorien

Anwendung

Reactant for:
  • Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
  • Preparation of cyclodextrin-containing polymers designed for gene delivery
  • Crosslinking of chick oviduct progesterone-receptor subunits

Vorsicht

The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.

Sonstige Hinweise

Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H315

Gefahreneinstufungen

Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCK3158
MKCK3156
MKCG2165
MKCD7400
MKCB1770V

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Choong Eun Jin et al.
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Carine F Djuika et al.
Scientific reports, 7(1), 4410-4410 (2017-07-02)
Artemisinins are the current mainstay of malaria chemotherapy. Their exact mode of action is an ongoing matter of debate, and several factors have recently been reported to affect an early stage of artemisinin resistance of the most important human malaria
Xiaoqiang Liu et al.
The Analyst, 136(24), 5204-5210 (2011-10-19)
An ultrasensitive electrochemical immmunosensor was demonstrated to be capable of detecting the hormone cortisol down to concentrations as low as 16 pg mL(-1). In addition, the immunosensor displayed a sensitivity of 1.6 μA pg(-1) mL(-1) and a linear range up
R A Aman et al.
The Journal of biological chemistry, 260(11), 6966-6973 (1985-06-10)
Glycosomes, the microbody-like organelles containing mainly glycolytic enzymes, were purified from the long slender bloodstream form of Trypanosoma brucei EATRO 110 monomorphic strain by an improved method in which the protozoa were frozen and thawed in 15% glycerol to free
K K Sharma et al.
Experimental eye research, 61(4), 413-421 (1995-10-01)
Alpha crystallin can function as a molecular chaperone in suppressing the heat-induced aggregation of other crystallins and proteins. During cataractogenesis, alpha-crystallin becomes a water-insoluble, high-molecular-weight, cross-linked aggregate. To determine whether the chaperone activity of alpha crystallin is lost during this
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Smart Oligonucleotide Delivery by Multifunctional Block Copolymers

Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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