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D2388

Sigma-Aldrich

Dimethyl-3,3′-Dithiopropionimidat -dihydrochlorid

powder

Synonym(e):

DTBP, Dimethyl-3,3′-dithiodipropionimidat -dihydrochlorid, Wang-Richards’ Reagens -dihydrochlorid

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About This Item

Empirische Formel (Hill-System):
C8H16N2O2S2 · 2HCl
CAS-Nummer:
38285-78-8
Molekulargewicht:
309.28
MDL-Nummer:
MFCD00043245
UNSPSC-Code:
12352116
PubChem Substanz-ID:
57654084
NACRES:
NA.22

Form

powder

Eignung der Reaktion

reagent type: cross-linking reagent

Löslichkeit

H2O: 50 mg/mL

Lagertemp.

2-8°C

SMILES String

Cl.Cl.COC(=N)CCSSCCC(=N)OC

InChI

1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H

InChIKey

CQBCVFHLZAVNPF-UHFFFAOYSA-N

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Anwendung

Reactant for:
  • Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
  • Preparation of cyclodextrin-containing polymers designed for gene delivery
  • Crosslinking of chick oviduct progesterone-receptor subunits

Vorsicht

The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.

Sonstige Hinweise

Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H315

Gefahreneinstufungen

Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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R A Aman et al.
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K K Sharma et al.
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