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Bis-MPA-NHBoc dendrimer
generation 4
Synonym(e):
Bis-MPA dendrimer, NHBoc functionalized dendrimer, PFD-G4-TMP-NH-Boc
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About This Item
Empfohlene Produkte
Form
solid
Qualitätsniveau
Mol-Gew.
generation 4
Anzahl Oberflächengruppen
48
Farbe
white to off-white
Lagertemp.
−20°C
Allgemeine Beschreibung
- Polymer architecture: Dendrimer
- Generation: 4
- End group functionality: Boc-protected amine
- No. surface groups: 48
- Calculated mol. wt.: 13576.80 g/mol
- Boc: tert-Butyloxycarbonyl
- Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid.
Anwendung
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrimers synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After boc deprotection, amine-functionalized dendrimers can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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