900919

Azidoacetic acid NHS ester

• Synonym(e): (2,5-Dioxopyrrolidin-1-yl) 2-azidoacetate, 1-[(Azidoacetyl)oxy]pyrrolidine-2,5-dione
• Empirische Formel (Hill-System): C₆H₆N₄O₄
• CAS-Nummer: 824426-32-6
• Molekulargewicht: 198.14
• MDL-Nummer: MFCD24452499
• UNSPSC-Code: 12352106
• NACRES: NA.22

Eigenschaften

• Form: powder or crystals
• Qualitätsniveau: 100
• Eignung der Reaktion: reagent type: cross-linking reagent
• Verfügbarkeit: available only in USA
• Lagertemp.: −20°C
• SMILES String: [N+](=[N-])=NCC(=O)ON1C(=O)CCC1=O
• InChI: 1S/C6H6N4O4/c7-9-8-3-6(13)14-10-4(11)1-2-5(10)12/h1-3H2
• InChIKey: FENNDBOWHRZLTQ-UHFFFAOYSA-N

Beschreibung

Anwendung

Azidoacetic acid NHS ester is a simple azido-containing reagent with an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines at pH 7-9 forming a stable amide bond. The azide allows for chemoselective ligation with an alkyne or cyclooctyne. It is generally used to functionalize amines and amino acids with azidoacetyl groups. It is generally used in click chemistry applications.

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Danger
• H-Sätze: H242
• P-Sätze: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Gefahreneinstufungen: Self-react. C
• Lagerklassenschlüssel: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable