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Ursprungszeugnis (CoO)/Analysenzertifikate (CoA)

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804347

3-nitro-N-[(3S)-tetrahydro-2-oxo-furanyl]-Benzeneacetamide

Name: 3-nitro-<I>N</I>-[(3<I>S</I>)-tetrahydro-2-oxo-furanyl]-Benzeneacetamide
Brand: ALDRICH

Synonym(e):

LasR inhibitor, LuxR activator

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About This Item

Empirische Formel (Hill-System):

C₁₂H₁₂N₂O₅

CAS-Nummer:

942296-29-9

Molekulargewicht:

264.23

UNSPSC-Code:

12352200

NACRES:

NA.22

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Sigma-Aldrich

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1,3,5-Tris-(brommethyl)-2,4,6-triethyl-benzol

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361437

cis-1,2-Cyclopentandiol

Sigma-Aldrich

663190

Ethyl-5-Methylindol-2-Carboxylat

Sigma-Aldrich

O9808

2-Indolinon

Sigma-Aldrich

737917

2,3,4,5,6-Pentafluorobenzylphosphonsäure

Sigma-Aldrich

374059

3-Brom-1,1,1-trifluoraceton

Sigma-Aldrich

776734

4-(2,3-Dihydro-1,3-dimethyl-1H-benzimidazol-2-yl)-N,N-dimethylbenzenamine

Sigma-Aldrich

233188

4′-(Trifluormethyl)acetophenon

Sigma-Aldrich

138096

Ethyl-5-chlor-2-indolcarboxylat

Form

solid

Lagertemp.

−20°C

Anwendung

PHL has varied activity depending on species, for example serving as either a strong LuxR-type receptor activator (e.g.: of LuxR in V. fischeri and of ExpR1 and ExpR2 in Pectobacterium carotovora) or a strong inhibitor (e.g.: of LasR in P. aeruginosa)

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Quorum sensing in bacterial species that use degenerate autoinducers can be tuned by using structurally identical non-native ligands.

Andrew G Palmer et al.

Chembiochem : a European journal of chemical biology, 12(1), 138-147 (2010-12-15)

Many bacteria use quorum sensing (QS) to regulate cell-density dependent phenotypes that play critical roles in the maintenance of their associations with eukaryotic hosts. In Gram-negative bacteria, QS is primarily controlled by N-acylated L-homoserine lactone (AHL) signals and their cognate

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

Grant D Geske et al.

Journal of the American Chemical Society, 129(44), 13613-13625 (2007-10-12)

Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There

Artikel

Quorum Sensing Modulators

Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediating certain symbioses.

Key Documents

3-nitro-N-[(3S)-tetrahydro-2-oxo-furanyl]-Benzeneacetamide

About This Item

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Eigenschaften

Form

Lagertemp.

Beschreibung

Anwendung

Sicherheitshinweise

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Dokumentation

Analysenzertifikate (COA)

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