747386
Poly(L-lactide), thiol terminated
average Mn 2,500, PDI ≤1.2
Synonym(e):
mercapto PLA, mercapto PLLA, thioPLA
About This Item
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Form
solid
Optische Aktivität
[α]22/D -138°, c = 0.5% in chloroform
Mol-Gew.
average Mn 2,500
Übergangstemp.
Tm 127-137 °C
PDI
≤1.2
Lagertemp.
2-8°C
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Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 3
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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Artikel
MALDI-TOF MS is a tool for confirming end group identity & transformations, verifying successful & complete conjugation. Functionalized polymers enable a quick & efficient route for synthesis of various polymer conjugates for many applications if apt end group is present.
Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.
The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).
Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "
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