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719900

Resomer^® RG 504 H, Poly(D,L-lactide-co-glycolide)

Name: Resomer<SUP>®</SUP> RG 504 H, Poly(<SC>D,L</SC>-lactide-<I>co</I>-glycolide)
Brand: ALDRICH

acid terminated, lactide:glycolide 50:50, M_w 38,000-54,000

Synonym(e):

RESOMER^® RG 504 H

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About This Item

Lineare Formel:

[C₃H₄O₂]_x[C₂H₂O₂]_y

CAS-Nummer:

26780-50-7

UNSPSC-Code:

12162002

NACRES:

NA.23

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Qualitätsniveau

200

Form

amorphous

Zufuhrverhältnis

lactide:glycolide 50:50

Mol-Gew.

M_w 38,000-54,000

Zeitrahmen für den Abbau

<3 months

Viskosität

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

Übergangstemp.

T_g 46-50 °C

Lagertemp.

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChIKey

LCSKNASZPVZHEG-UHFFFAOYSA-N

Anwendung

Resomer^® RG 504 H, Poly(D, L-Lactide-co-Glycolide) can be used to fabricate a biodegradable hemostyptic device for safe and locally controlled release of thrombin which promotes local blood clot formation.

It can be used to preparepolymer nanospheres for encapsulating CuO, to form stimuli-responsivemultifunctional nanocarriers.

Rechtliche Hinweise

Product of Evonik

RESOMER is a registered trademark of Evonik Rohm GmbH

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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In-vitro, ex-vivo, and in-vivo evaluation of buprenorphine HCl release from an in situ forming gel of PLGA-PEG-PLGA using N‑methyl‑2‑pyrrolidone as solvent.

Hossein Kamali et al.

Materials science & engineering. C, Materials for biological applications, 96, 561-575 (2019-01-05)

An in situ forming gel (ISFG) of buprenorphine (BP) was prepared using PLGA-PEG-PLGA (triblock) and N‑methyl‑2‑pyrrolidone as solvent for decreasing the initial burst release. Supercritical CO2 method was used for ring opening polymerization of triblock. The optimum formulation of ISFG

An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery.

Niranjan G Kotla et al.

Nanomaterials (Basel, Switzerland), 9(9) (2019-09-05)

There is a pressing clinical need for advanced colon-specific local drug delivery systems that can provide major advantages in treating diseases associated with the colon, such as inflammatory bowel disease (IBD) and colon cancer. A precise colon targeted drug delivery

Effect of water on exenatide acylation in poly(lactide-co-glycolide) microspheres.

Rongcai Liang et al.

International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)

Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative

Induction of long-lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide-co-glycolide) microparticles.

Shu-Chun Chuang et al.

Parasites & vectors, 6, 34-34 (2013-02-13)

Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or

Development of novel cationic chitosan-and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol.

Vanna Sanna et al.

International journal of nanomedicine, 7, 5501-5516 (2012-10-25)

Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may

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Wichtige Dokumente

Resomer® RG 504 H, Poly(D,L-lactide-co-glycolide)

acid terminated, lactide:glycolide 50:50, Mw 38,000-54,000

About This Item

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Eigenschaften

Qualitätsniveau

Form

Zufuhrverhältnis

Mol-Gew.

Zeitrahmen für den Abbau

Viskosität

Übergangstemp.

Lagertemp.

InChI

InChIKey

Beschreibung

Anwendung

Rechtliche Hinweise

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Sicherheitshinweise

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Dokumentation

Analysenzertifikate (COA)

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Resomer^® RG 504 H, Poly(D,L-lactide-co-glycolide)

acid terminated, lactide:glycolide 50:50, M_w 38,000-54,000