707929

4-Isochinolinboronsäure

• Synonym(e): Isochinolin-4-boronsäure
• Empirische Formel (Hill-System): C₉H₈BNO₂
• CAS-Nummer: 192182-56-2
• Molekulargewicht: 172.98
• MDL-Nummer: MFCD03412093
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 329762755

Eigenschaften

• Form: solid
• mp (Schmelzpunkt): 230-234 °C
• Lagertemp.: 2-8°C
• SMILES String: OB(O)c1cncc2ccccc12
• InChI: 1S/C9H8BNO2/c12-10(13)9-6-11-5-7-3-1-2-4-8(7)9/h1-6,12-13H
• InChIKey: GDTOUTKTCGPAGY-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

May contain varying amounts of anhydride

Anwendung

Reactant for:

• Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases
• Preparation of tetrabutylammonium trifluoroborates
• Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
• Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain
• Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines
• Synthesis of antagonists of bacterial quorum sensing
• Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves