694509

3,3-Difluorpyrrolidin -hydrochlorid

97%

• Empirische Formel (Hill-System): C₄H₇F₂N · HCl
• CAS-Nummer: 163457-23-6
• Molekulargewicht: 143.56
• MDL-Nummer: MFCD03788948
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329761667
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 133-136 °C
• SMILES String: Cl.FC1(F)CCNC1
• InChI: 1S/C4H7F2N.ClH/c5-4(6)1-2-7-3-4;/h7H,1-3H2;1H
• InChIKey: YYVPZQADFREIFR-UHFFFAOYSA-N

Beschreibung

Anwendung

3,3-Difluoropyrrolidine hydrochloride can be used as a building block in the synthesis of:

• Triazole substituted prolyl difluoropyrrolidines as potential inhibitors of dipeptidyl peptidase-4.
• Dual leucine zipper kinase (DLK) inhibitors.

It can be also used as a reactant in the preparation of cyclic and acyclic β-aminofluoroalkenes via allylic amination using the Pd catalyst.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315 - H319 - H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves