540072

(R)-(−)-Epichlorhydrin

99%

• Synonym(e): (R)-(−)-2-Chlormethyl-oxiran
• Empirische Formel (Hill-System): C₃H₅ClO
• CAS-Nummer: 51594-55-9
• Molekulargewicht: 92.52
• Beilstein: 1420785
• EG-Nummer: 424-280-2
• MDL-Nummer: MFCD00077759
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24878437
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 3.29 (vs air)
• Qualitätsniveau: 100
• Dampfdruck: 10 mmHg ( 16.6 °C)
• Assay: 99%
• Optische Aktivität: [α]20/D −34°, c = 1 in methanol
• Optische Reinheit: ee: 98% (GLC)
• Selbstzündungstemp.: 772 °F
• Expl.-Gr.: 21 %
• Brechungsindex: n20/D 1.438 (lit.)
• bp: 114 °C (lit.)
• Dichte: 1.180 g/mL at 20 °C (lit.)
• SMILES String: ClC[C@H]1CO1
• InChI: 1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m0/s1
• InChIKey: BRLQWZUYTZBJKN-VKHMYHEASA-N

Beschreibung

Anwendung

Building block for the synthesis of a key intermediate in the synthesis of stable PGI₂ analogue UT-15.

Used in the synthesis of chiral morpholines and dioxanes via a Mitsunobu diol-cyclization. Chiral building block in the enantioselective synthesis of trans-2,4-disubstituted piperidines.

Rechtliche Hinweise

Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H226,H301 + H311 + H331,H314,H317,H350
• P-Sätze: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 89.6 °F - closed cup
• Flammpunkt (°C): 32 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter