357995

Sclareol

98%

• Synonym(e): (1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol
• Empirische Formel (Hill-System): C₂₀H₃₆O₂
• CAS-Nummer: 515-03-7
• Molekulargewicht: 308.50
• Beilstein: 2054148
• EG-Nummer: 208-194-0
• MDL-Nummer: MFCD00869558
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24861955
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Optische Aktivität: [α]25/D −13°, c = 4 in carbon tetrachloride
• bp: 218-220 °C/19 mmHg (lit.)
• mp (Schmelzpunkt): 95-100 °C (lit.)
• Funktionelle Gruppe: hydroxyl
• SMILES String: CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@](C)(O)[C@@H]2CC[C@@](C)(O)C=C
• InChI: 1S/C20H36O2/c1-7-18(4,21)13-9-16-19(5)12-8-11-17(2,3)15(19)10-14-20(16,6)22/h7,15-16,21-22H,1,8-14H2,2-6H3/t15-,16+,18-,19-,20+/m0/s1
• InChIKey: XVULBTBTFGYVRC-HHUCQEJWSA-N

Beschreibung

Allgemeine Beschreibung

Sclareol, a diterpene compound with a labdane skeleton, is mainly used as a raw material in the fragrance industry. It shows potent cytotoxic and cytostatic effect in human leukemic cell lines.

Anwendung

Sclareol may be used as a starting material in the synthesis of ambergris fragrance chemicals such as ambraoxide, ambrox, methylambraoxide, ambracetal, ambraketal and epiambraketal. It may also be used in the synthesis of (+)-galanolactone, (-)-8-epi-galanolactone and (+)-labdienedial.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)