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Merck

318434

Sigma-Aldrich

3,3′-Dipropylthiacarbocyaniniodid

98%

Synonym(e):

3-Propyl-2-[3-[3-propyl-2(3H)-benzothiazolyliden]-1-propenyl]-benzothiazolium-iodid, DiSC3(3)

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About This Item

Empirische Formel (Hill-System):
C23H25IN2S2
CAS-Nummer:
Molekulargewicht:
520.49
Beilstein:
3842440
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47

Assay

98%

Form

crystalline powder

mp (Schmelzpunkt)

288 °C (dec.) (lit.)

Löslichkeit

chloroform/methanol: 10 mg/mL, clear

λmax

559 nm

ε (Extinktionskoeffizient)

163120 at 599 nm in methanol at 0.00463 g/L
17425 at 298 nm in methanol at 0.00463 g/L
40246 at 220 nm in methanol at 0.00463 g/L

Fluoreszenz

λex 559 nm; λem 575 nm in methanol

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

[I-].CCCN1C(\Sc2ccccc12)=C\C=C\c3sc4ccccc4[n+]3CCC

InChI

1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23;/h5-15H,3-4,16-17H2,1-2H3;1H/q+1;/p-1

InChIKey

JGTCEHAVVINOPG-UHFFFAOYSA-M

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Allgemeine Beschreibung

3,3′-Dipropylthiacarbocyanine iodide is a carbocyanine fluorescent dye sensitive to membrane potential. This cyanine dye plays a vital role as an optical probe of membrane potential. An increase in the fluorescence intensity of the dye indicates depolarization of the plasma membrane potential.

Anwendung

3,3′-Dipropylthiacarbocyanine iodide has been used to determine bacterial membrane permeability by the effect of electrochemical scaffold treatment.

Biochem./physiol. Wirkung

The embrane potential sensitive dye, 3,3′dipropylthiacarbocyanine iodide enters only depolarized cells, where it binds reversibly to lipid-rich intracellular components.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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