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167134

Sigma-Aldrich

Bromhydrochinon

97%

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About This Item

Lineare Formel:
BrC6H3(OH)2
CAS-Nummer:
583-69-7
Molekulargewicht:
189.01
EG-Nummer:
209-516-2
MDL-Nummer:
MFCD00041747
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24850194
NACRES:
NA.22

Assay

97%

mp (Schmelzpunkt)

112-116 °C (lit.)

SMILES String

Oc1ccc(O)c(Br)c1

InChI

1S/C6H5BrO2/c7-5-3-4(8)1-2-6(5)9/h1-3,8-9H

InChIKey

REFDOIWRJDGBHY-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

Bromohydroquinone was used in the synthesis of Π-conjugated polymers composed of alkyl carbazole/dialkoxyphenylene and squaraine units via Sonogashira cross-coupling reactions. It was used in the preparation of 2-bromobenzoquinone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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3,4-Dihydro-2H-Pyran 97%

Sigma-Aldrich

D106208

3,4-Dihydro-2H-Pyran

Hydrochinon ReagentPlus®, ≥99%

Sigma-Aldrich

H9003

Hydrochinon

T J Monks et al.
Molecular pharmacology, 34(1), 15-22 (1988-07-01)
The formation of potentially reactive thiols has been postulated to play a role in the nephrotoxicity caused by a number of glutathione and/or cysteine conjugates. However, the inherent reactivity of such compounds has precluded both their identification in biological systems
T J Monks et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(5), 553-559 (1985-09-01)
Incubation of either o-bromophenol or 2-bromohydroquinone with rat liver microsomes and 0.25 mM 35S-glutathione (GSH) gave rise to several isomeric 35S-GSH conjugates. A mixture of these isomeric GSH conjugates was prepared chemically and two were purified by HPLC; 1H-NMR spectroscopy
R G Schnellmann
Toxicology and applied pharmacology, 99(1), 11-18 (1989-06-01)
2-Bromohydroquinone (BHQ) plays an important role in bromobenzene-induced nephrotoxicity and is a model toxic hydroquinone. Since BHQ has a quinone nucleus and various quinones have been shown to produce cytotoxicity via oxidative stress, the goal of this study was to
G W Miller et al.
Toxicology and applied pharmacology, 125(2), 192-197 (1994-04-01)
We have previously shown that strychnine mimics the cytoprotective properties of glycine in renal proximal tubule (RPT) suspensions exposed to antimycin A (AA). The aims of this study were to determine whether the cytoprotective properties of strychnine applied to various
S S Lau et al.
Biochemical and biophysical research communications, 152(1), 223-230 (1988-04-15)
2-Bromo-(diglutathion-Syl)hydroquinone (2-Br-[diGSyl]HQ) is a more potent nephrotoxicant than any of three mono-substituted isomers. The reason for this differential toxicity is unknown. We now report that the rate of uptake of 2-Br-(diGSyl)HQ, 2-Br-3-(GSyl)HQ, 2-Br-5-(GSyl)-HQ and 2-Br-6(GSyl)HQ by kidney slices was 2.4
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