145505

α-Cyano-4-hydroxyzimtsäure

97%

• Synonym(e): alpha-Cyano-4-hydroxycinnamic acid, α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA
• Lineare Formel: HOC₆H₄CH=C(CN)CO₂H
• CAS-Nummer: 28166-41-8
• Molekulargewicht: 189.17
• Beilstein: 3271427
• EG-Nummer: 248-879-1
• MDL-Nummer: MFCD00004204
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848731
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: powder
• mp (Schmelzpunkt): 245-250 °C (lit.)
• Löslichkeit: methanol: soluble 50 mg/mL, clear to slightly hazy, light yellow to yellow
• Funktionelle Gruppe: carboxylic acid; nitrile
• Lagertemp.: 2-8°C
• SMILES String: OC(=O)\C(=C\c1ccc(O)cc1)C#N
• InChI: 1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
• InChIKey: AFVLVVWMAFSXCK-VMPITWQZSA-N

Beschreibung

Allgemeine Beschreibung

α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.

Anwendung

α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1B
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves