142360

4-Benzylpiperidin

99%

• Synonym(e): Phenyl-4-piperidyl-methan
• Empirische Formel (Hill-System): C₁₂H₁₇N
• CAS-Nummer: 31252-42-3
• Molekulargewicht: 175.27
• Beilstein: 132339
• EG-Nummer: 250-535-0
• MDL-Nummer: MFCD00006006
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848521
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 99%
• Brechungsindex: n20/D 1.537 (lit.)
• bp: 279 °C (lit.)
• mp (Schmelzpunkt): 6-7 °C (lit.)
• Dichte: 0.997 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: phenyl
• SMILES String: C1CC(CCN1)Cc2ccccc2
• InChI: 1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2
• InChIKey: ABGXADJDTPFFSZ-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Htr2a(29595) , Htr2c(25187)

Beschreibung

Allgemeine Beschreibung

4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence.

Anwendung

4-Benzylpiperidine was used to study the metabolism of 1,3-butadiene and its oxidized metabolites in perfused livers of male B6C3F1 mice and Sprague-Dawley rats.

Reactant for synthesis of:

• Antiproliferatives
• GABA uptake inhibitors
• Pyridines
• Histamine H3 antagonists
• Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
• Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution

Biochem./physiol. Wirkung

4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 233.6 °F - closed cup
• Flammpunkt (°C): 112 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter