122564

Mechlorethamin -hydrochlorid

98%

• Synonym(e): 2-Chlor-N-(2-chlorethyl)-N-methylethanamin, N-Methylbis-(2-chlorethyl)-amin -hydrochlorid, Bis-(2-chlorethyl)-methylamin, Stickstofflost
• Lineare Formel: (ClCH₂CH₂)₂NCH₃·HCl
• CAS-Nummer: 55-86-7
• Molekulargewicht: 192.51
• EG-Nummer: 200-246-0
• MDL-Nummer: MFCD00012517
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24847496
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 108-111 °C (lit.)
• Löslichkeit: H₂O: very soluble; alcohol: soluble
• Funktionelle Gruppe: amine; chloro
• SMILES String: Cl.CN(CCCl)CCCl
• InChI: 1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H
• InChIKey: QZIQJVCYUQZDIR-UHFFFAOYSA-N

Beschreibung

Anwendung

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem./physiol. Wirkung

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H300 + H310,H314,H340,H350,H360D
• P-Sätze: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges