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MYC

v-myc avian myelocytomatosis viral oncogene homolog

Synonyme:
MRTL, MYCC, bHLHe39, c-Myc
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

Produktnummer
Beschreibung
Spezies
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Speziesreaktivität
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-c-Myc-Antikörper, monoklonaler Antikörper der Maus in Maus hergestellte Antikörper, clone 9E10, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-Myc-Tag-Antikörper, Klon 4A6, clone 4A6, Upstate®, from mouse,
Speziesreaktivität
human
Anwendung
ChIP
immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-cMyc in Kaninchen hergestellte Antikörper, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

microarray

western blot
Anti-Myc-Tag-Antikörper, Klon 9E10, Alexa Fluor 488-Konjugat, clone 9E10, Upstate®, from mouse,
Speziesreaktivität
all
Anwendung
immunocytochemistry
western blot

Proteins

Produktnummer
Beschreibung
Spezies
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MYC,
Spezies
human
MISSION® esiRNA, targeting mouse Myc,
Spezies
mouse