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KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonyme:
C-Kit, CD117, PBT, SCFR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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ELISA

Produktnummer
Beschreibung
Spezies
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Spezies
human
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho-c-Kit-(Tyr568/Tyr570)-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
human
Anwendung
western blot
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-CD117 (c-Kit) Antibody, clone 2C11, clone 2C11, from mouse,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
western blot
Anti-CD117 Antibody, clone ACK2, clone ACK2, Chemicon®, from rat,
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-KIT antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Imatinib, ,
Spezies
human
Pazopanib, ,
Spezies
human
Dasatinib, ≥98% (HPLC),
Spezies
human
Dasatinib, ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Spezies
human
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Spezies
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Spezies
human
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
c-KIT (N822K), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Kit,
Spezies
mouse
MISSION® esiRNA, targeting human KIT,
Spezies
human