Direkt zum Inhalt
Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonyme:
DNMT3A2, M.HsaIIIA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
ELISA
western blot
Anti-DNMT3A2 Antibody, from rabbit,
Speziesreaktivität
human
Anwendung
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-DNMT3A antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
5-Aza-2′-Desoxycytidin, ≥97%,
Spezies
human
Azacitidin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
5-Azacytidin, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Spezies
human
Azacitidin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
5-Azacytidin, ≥98% (HPLC),
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Spezies
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human DNMT3A,
Spezies
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Spezies
mouse