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1650006

USP

Tetracaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C15H24N2O2 · HCl
Numéro CAS:
136-47-0
Poids moléculaire :
300.82
Numéro MDL:
MFCD00038912
Code UNSPSC :
41116107
ID de substance PubChem :
329751254
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

tetracaine

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

Clé InChI

PPWHTZKZQNXVAE-UHFFFAOYSA-N

Informations sur le gène

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tetracaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Gel
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Ointment
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Aerosol®
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Solution
  • Lidocaine, Racepinephrine, and Tetracaine Hydrochlorides Compounded Topical Gel
  • Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Ointment
  • Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Topical Powder
Topical ophthalmic anesthetic; used for spinal anesthesia

Actions biochimiques/physiologiques

Blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations légales

Aerosol is a registered trademark of Cytec Technology Corp.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

T0500000

Tetracaine hydrochloride, European Pharmacopoeia (EP) Reference Standard

Y0001002

Tetracaine for system suitability, European Pharmacopoeia (EP) Reference Standard

1649991

Tetracaine, United States Pharmacopeia (USP) Reference Standard

1650017

Tetracaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1650028

Tetracaine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1466572

4-Nitrobenzoic acid, United States Pharmacopeia (USP) Reference Standard

Y0002117

Tetracaine, European Pharmacopoeia (EP) Reference Standard

PHR9019

4-Aminobenzyl alcohol, reference material

PHR9024

3-Aminobenzyl alcohol, reference material

PHR2236

Tetracaine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2261

Tetracaine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2339

4-Nitrobenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3140

Tetracaine, pharmaceutical secondary standard, certified reference material

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301,H319,H336

Classification des risques

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Genea Edwards et al.
Biochimie, 105, 99-109 (2014-07-12)
To identify the sphingolipid and ceramide species and their quantitative differences between normotensive and hypertensive intraocular pressure states in DBA/2J mouse aqueous humor (AH). Normotensive and hypertensive AH was sampled from mice by paracentesis. Lipid extraction was performed using modifications
Akihiro Tanaka et al.
Antimicrobial agents and chemotherapy, 58(8), 4380-4383 (2014-05-21)
We have reported significantly higher convulsion prevalence in patients treated with cefepime than in those treated with meropenem. Additionally, cefepime-associated convulsions were found only in patients with brain disorders, not renal failure. Here, we compared the convulsive liability of cefepime
Sara Brittingham et al.
Investigative ophthalmology & visual science, 55(12), 8371-8376 (2014-12-04)
To compare the occurrence rate and depth of the demarcation line and topographical outcome after corneal cross-linking (CXL) for keratoconus using two different treatment protocols. A retrospective analysis of 131 eyes with progressive keratoconus treated with CXL using riboflavin and
Elisa Cinotti et al.
American journal of ophthalmology, 159(2), 324-333 (2014-12-03)
To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of conjunctival tumors. Prospective study, observational case series. We prospectively evaluated the reflectance confocal
Angel Nava-Castañeda et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 31(2), 106-113 (2014-11-05)
The aim of the study was to evaluate the effect of 3 subconjunctival bevacizumab injections in patients with an early corneal pterygium recurrence. This study was a nonrandomized single center trial. Patients with an early corneal pterygium recurrence were selected.
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