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1462006

USP

Nicotinamide

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Acide nicotinique amide, Acide pyridine-3-carboxylique amide, Vitamine PP, Vitamine B3

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About This Item

Formule empirique (notation de Hill):
C6H6N2O
Numéro CAS:
98-92-0
Poids moléculaire :
122.12
Numéro Beilstein :
383619
Numéro MDL:
MFCD00006395
Code UNSPSC :
41116107
ID de substance PubChem :
329750553
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

nicotinamide

Fabricant/nom de marque

USP

Pf

128-131 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

Clé InChI

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Niacinamide USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, Niacin standard solution, standard niacinamide stock solution, and sample solution for assay, performance, and strength analysis according to the given below monographs and general chapters of United States Pharmacopeia (USP):
  • Niacinamide
  • Niacinamide Tablets
  • Niacinamide Injection
  • 〈441〉 Niacin or Niacinamide Assay

Actions biochimiques/physiologiques

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

N0600000

Nicotinamide, European Pharmacopoeia (EP) Reference Standard

E2400000

Ethylnicotinamide, European Pharmacopoeia (EP) Reference Standard

BP460

Nicotinamide, British Pharmacopoeia (BP) Reference Standard

BP1104

N-(2-Hydroxyethyl)isonicotinamide nitric ester, British Pharmacopoeia (BP) Reference Standard

PHR2089

Nicotinamide Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2090

Nicotinamide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2088

Nicotinamide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2087

Nicotinamide Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

302.0 °F - closed cup

Point d'éclair (°C)

150 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Sigma-Aldrich

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Niacinamide Injection
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Patients with radioactive iodine ((131)I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis because of the absence of effective treatment options. In this study, we assessed the efficacy and safety of orally administered sorafenib in the treatment
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Nicotinamide adenine dinucleotide (NAD+) biosynthesis from nicotinamide is used by mammalian cells to replenish their NAD+ stores and to avoid unwanted nicotinamide accumulation. Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the key enzyme in this biosynthetic pathway, almost invariably leads to
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