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1294207

USP

Glucosamine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

D-(+)-Glucosamine hydrochloride, 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C6H13NO5 · HCl
Numéro CAS:
66-84-2
Poids moléculaire :
215.63
Numéro Beilstein :
4157370
Numéro MDL:
MFCD00135831
Code UNSPSC :
41116107
ID de substance PubChem :
329749944
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

glucosamine

Fabricant/nom de marque

USP

Pf

190-194 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

Clé InChI

QKPLRMLTKYXDST-NSEZLWDYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glucosamine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Glucosamine and Chondroitin Sulfate Sodium Tablets
  • Glucosamine and Methylsulfonylmethane Tablets
  • Glucosamine Hydrochloride
  • Glucosamine Sulfate Potassium Chloride
  • Glucosamine Sulfate Sodium Chloride
  • Glucosamine Tablets
  • Glucosamine, Chondroitin Sulfate Sodium, and Methylsulfonylmethane Tablets

Actions biochimiques/physiologiques

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1223

2-Methylpyrazine, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001376

2-Methylpyrazine, European Pharmacopoeia (EP) Reference Standard

Y0001381

Glucosamine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001407

Glucosamine sulfate sodium chloride, European Pharmacopoeia (EP) Reference Standard

Y0001406

Glucosamine hydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1432

N-Acétyl-D-glucosamine, Pharmaceutical Secondary Standard; Certified Reference Material

1010022

N-Acétyl-D-glucosamine, United States Pharmacopeia (USP) Reference Standard

PHR2290

Glucosamine Impurity B, Pharmaceutical Secondary Standard; Certified Reference Standard

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Oshra Betzer et al.
ACS nano, 8(9), 9274-9285 (2014-08-19)
A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a
Antonella Denise Losinno et al.
Autophagy, 17(2), 439-456 (2020-01-28)
Cruzipain, the major cysteine protease of the pathogenic protozoa Trypanosoma cruzi, is an important virulence factor that plays a key role in the parasite nutrition, differentiation and host cell infection. Cruzipain is synthesized as a zymogen, matured, and delivered to
Ji-Sun Hwang et al.
Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)
This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)
Khadijeh Jamialahmadi et al.
Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)
Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in
Viktor Chesnokov et al.
Cancer cell international, 14, 45-45 (2014-06-17)
We have reported that the glucosamine suppressed the proliferation of the human prostate carcinoma cell line DU145 through inhibition of STAT3 signaling. DU145 cells autonomously express IL-6 and the IL-6/STAT3 signaling is activated. IL-6 receptor subunits are subject to N-glycosylation
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