1134357

Cisplatin

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
• Formule linéaire : Pt(NH₃)₂Cl₂
• Numéro CAS: 15663-27-1
• Poids moléculaire : 300.05
• Numéro MDL: MFCD00011623
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749409
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: cisplatin
• Fabricant/nom de marque: USP
• Pf: 270 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: N.N.Cl[Pt]Cl
• InChI: 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
• Clé InChI: LXZZYRPGZAFOLE-UHFFFAOYSA-L

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cisplatin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):

• Cisplatin
• Cisplatin for Injection
• Carboplatin Injection

Actions biochimiques/physiologiques

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H300 - H315 - H317 - H319 - H334 - H335 - H350
• Conseils de prudence: P201 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable