1091108

Capsaicin

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 8-Methyl-N-vanillyl-trans-6-nonenamide
• Formule linéaire : (CH₃)₂CHCH=CH(CH₂)₄CONHCH₂C₆H₃-4-(OH)-3-(OCH₃)
• Numéro CAS: 404-86-4
• Poids moléculaire : 305.41
• Beilstein: 2816484
• Numéro MDL: MFCD00017259
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749225
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: capsaicin
• Fabricant/nom de marque: USP
• Pf: 62-65 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• Clé InChI: YKPUWZUDDOIDPM-SOFGYWHQSA-N
• Informations sur le gène: human ... TRPV1(7442)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):

• Capsaicin
• Capsicum Oleoresin
• Capsicum
• Ginger Tincture

Actions biochimiques/physiologiques

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Prototype vanilloid receptor agonist; neurotoxin. Active component of chili peppers.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H300,H315,H317,H318,H334,H335
• Conseils de prudence: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Classification des risques: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 235.4 °F - closed cup
• Point d'éclair (°C): 113 °C - closed cup